Document Detail

Long term favorable prognostic value of negative treadmill echocardiogram in the setting of abnormal treadmill electrocardiogram: a 95 month median duration follow-up study.
MedLine Citation:
PMID:  18650063     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of this retrospective study was to assess if negative treadmill echocardiographic (NTME) results retained their favorable prognosis over a long period of follow-up (median, 95 months) in the setting of ischemic stress electrocardiographic (ISECG) results. METHODS: Consecutive patients with NTME results were analyzed as 2 groups (those with ISECG results and those with normal stress electrocardiographic results). Patients were followed up for a median duration of 95 months to identify major adverse cardiac events (MACEs), including all-cause death, myocardial infarction, and coronary revascularization. RESULTS: Six hundred seventy-seven patients fulfilled the inclusion criteria. Fifty-eight patients had MACEs (8.6%). The annual event rate was 1%. There was an increased unadjusted rate of MACEs among patients with ISECG results (15% vs 8%; P = .025). After adjusting for clinical and stress variables, ISECG results were not independently predictive of MACEs (P = .2). Female gender, prior coronary artery disease, metabolic equivalents achieved, and chest pain at stress were the independent predictors of MACEs. CONCLUSIONS: Patients with NTME results had excellent long-term outcomes, regardless of ISECG results, over a median 95-month follow-up period. The findings of this study reaffirm the importance of benign long-term outcomes in the setting of good exercise capacity.
Mouaz Al-Mallah; Fadi Alqaisi; Abdulilah Arafeh; Rachid Lakhdar; Rania Al-Tamsheh; Karthik Ananthasubramaniam
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Publication Detail:
Type:  Journal Article     Date:  2008-07-23
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  21     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-03     Completed Date:  2009-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1018-22     Citation Subset:  IM    
Henry Ford Hospital, Heart and Vascular Institute, Detroit, Michigan, USA.
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MeSH Terms
Aged, 80 and over
Cardiovascular Diseases / mortality*,  ultrasonography*
Echocardiography / statistics & numerical data*
Exercise Test / statistics & numerical data*
Follow-Up Studies
Michigan / epidemiology
Reproducibility of Results
Retrospective Studies
Risk Assessment / methods*
Risk Factors
Sensitivity and Specificity
Survival Analysis
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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