| Long-term exposure to indoor air pollution and wheezing symptoms in infants. | |
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MedLine Citation:
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PMID: 20028431 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Long-term exposure to air pollution is suspected to cause recurrent wheeze in infants. The few previous studies have had ambiguous results. The objective of this study was to estimate the impact of measured long-term exposure to indoor air pollution on wheezing symptoms in infants. We monitored wheezing symptoms in diaries for a birth cohort of 411 infants. We measured long-term exposure to nitrogen oxides (NO(x)), NO(2), formaldehyde, PM(2.5) and black smoke in the infants' bedrooms and analyzed risk associations during the first 18 months of life by logistic regression with the dichotomous end-point 'any symptom-day' (yes/no) and by standard linear regression with the end-point 'number of symptom-days'. The results showed no systematic association between risk for wheezing symptoms and the levels of these air pollutants with various indoor and outdoor sources. In conclusion, we found no evidence of an association between long-term exposure to indoor air pollution and wheezing symptoms in infants, suggesting that indoor air pollution is not causally related to the underlying disease. Practical Implications Nitrogen oxides, formaldehyde and fine particles were measured in the air in infants' bedrooms. The results showed no evidence of an association between long-term exposure and wheezing symptoms in the COPSAC birth cohort. |
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Authors:
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O Raaschou-Nielsen; M N Hermansen; L Loland; F Buchvald; C B Pipper; M Sørensen; S Loft; H Bisgaard |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-10-14 |
Journal Detail:
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Title: Indoor air Volume: 20 ISSN: 1600-0668 ISO Abbreviation: Indoor Air Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-22 Completed Date: 2010-08-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9423515 Medline TA: Indoor Air Country: Denmark |
Other Details:
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Languages: eng Pagination: 159-67 Citation Subset: IM |
Affiliation:
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Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen Ø, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Air Pollution, Indoor
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adverse effects* Denmark Humans Infant Infant, Newborn Inhalation Exposure / adverse effects* Nitrogen Oxides / adverse effects, analysis Prospective Studies Respiratory Sounds / etiology, physiopathology* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Nitrogen Oxides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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