Document Detail


Long-term effects of supervised exercise training on walking capacity and quality of life in patients with intermittent claudication.
MedLine Citation:
PMID:  18690592     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Supervised exercise training has been shown to improve walking capacity in several studies of patients with intermittent claudication. However, data on long-term outcome are quite limited. The aim of this prospective study was to evaluate long-term effects of supervised exercise training on walking capacity and quality of life in patients with intermittent claudication. Patients and methods: Sixty-seven consecutive patients with intermittent claudication who completed a supervised 12-week exercise training program were asked for follow up evaluation 39 +/- 20 months after program completion. Pain-free walking distance (PWD) and maximum walking distances (MWD) were assessed by treadmill test and several questionnaires. Results: Forty (60%) patients agreed to participate, 22 (33%) refused participation, and 5 (7%) died during follow-up. PWD and MWD significantly improved at completion of 12-weeks supervised exercise training as compared to baseline (PWD 114 +/- 100 vs. 235 +/- 248, p = 0.002; MWD 297 +/- 273 vs. 474 +/- 359, p = 0.001). Improvement of PWD and MWD could be maintained at follow up (197 +/- 254, p = 0.014; 390 +/- 324, p = 0.035, respectively) with non-smokers showing significantly better sustained PWD and MWD improvement as compared to baseline. Overall, walking capacity correlated with functional status of quality of life. Conclusions: Major findings of this investigation were that improvement in walking capacity is sustained after completion of supervised exercise training program with best results in patients who quitted or never smoked. Improved walking capacity is associated with increased functional status of quality of life.
Authors:
H Keo; E Grob; F Guggisberg; J Widmer; I Baumgartner; J-P Schmid; C Kalka; H Saner
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  VASA. Zeitschrift für Gefässkrankheiten     Volume:  37     ISSN:  0301-1526     ISO Abbreviation:  VASA     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-11     Completed Date:  2008-10-16     Revised Date:  2012-10-19    
Medline Journal Info:
Nlm Unique ID:  0317051     Medline TA:  Vasa     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  250-6     Citation Subset:  IM    
Affiliation:
Swiss Cardiovascular Center, Division of Angiology, Inselspital Bern, University Hospital and University of Bern, Switzerland. keo.hakhong@insel.ch
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Exercise Test
Exercise Therapy*
Exercise Tolerance*
Female
Follow-Up Studies
Humans
Intermittent Claudication / physiopathology,  therapy*
Male
Middle Aged
Prospective Studies
Quality of Life*
Questionnaires
Recovery of Function
Smoking / adverse effects
Smoking Cessation
Time Factors
Treatment Outcome
Walking*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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