| Long-term effects of a reduced fat diet intervention on cardiovascular disease risk factors in individuals with glucose intolerance. | |
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MedLine Citation:
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PMID: 14739050 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The long-term effects on cardiovascular disease risk factors of a reduced fat (RF), ad libitum diet were compared with usual diet (control, CD) in glucose intolerance individuals. Participants were 136 adults aged > or =40 years with 'glucose intolerance' (2h blood glucose 7-11.0 mmol/l) detected at a Diabetes Survey who completed at 1 year intervention study of reduced fat, ad libitum diet versus usual diet. They were re-assessed at 2, 3 and 5 years. Main outcome measures were blood pressure, serum concentrations of total cholesterol, HDL and LDL cholesterol, total cholesterol:HDL ratio, triglycerides and body weight. The reduced fat diet lowered total cholesterol (P<0.01), LDL cholesterol (P< or =0.05), total cholesterol:HDL ratio (P< or =0.05), body weight (P<0.01) and systolic blood pressure (P< or =0.05) initially and diastolic blood pressure (P<0.01) long-term. No significant changes occurred in HDL cholesterol or triglycerides. In the more compliant 50% of the intervention group, systolic and diastolic blood pressure levels and body weight were lower at 1, 2 and 3 years (P<0.05). It was concluded that a reduced fat ad libitum diet has short-term benefits for cholesterol, body weight and systolic blood pressure and long-term benefits for diastolic blood pressure without significantly effecting HDL cholesterol and triglycerides despite participants regaining their lost weight. |
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Authors:
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Sarah J Ley; Patricia A Metcalf; Robert K R Scragg; Boyd A Swinburn |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Diabetes research and clinical practice Volume: 63 ISSN: 0168-8227 ISO Abbreviation: Diabetes Res. Clin. Pract. Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-01-23 Completed Date: 2004-09-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8508335 Medline TA: Diabetes Res Clin Pract Country: Ireland |
Other Details:
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Languages: eng Pagination: 103-12 Citation Subset: IM |
Affiliation:
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Department of Community Health, University of Auckland, Private Bag 92019, Auckland, New Zealand. sarah@dietician.co.nz |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure Body Weight Cardiovascular Diseases / prevention & control* Cholesterol / blood Cholesterol, HDL / blood Cholesterol, LDL / blood Diastole Diet, Fat-Restricted* Female Glucose Intolerance* Humans Male Middle Aged Patient Compliance Risk Factors Systole Triglycerides / blood Weight Loss |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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