Document Detail


Long-term effects of daily hemodialysis on vascular access outcomes: a prospective controlled study.
MedLine Citation:
PMID:  23016876     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Daily hemodialysis has been associated with surrogate markers of improved survival among hemodialysis patients. A potential disadvantage of daily hemodialysis is that frequent vascular access cannulations may affect long-term vascular access patency. The study design was a 4-year, nonrandomized, contemporary control, prospective study of 77 subjects in either 3-h daily hemodialysis (six 3-h dialysis treatments weekly; n = 26) or conventional dialysis (three 4-h dialysis treatments weekly; n = 51). Outcomes of interest were vascular access procedures (fistulagram, thrombectomy and access revision). Total access procedures (fistulagram, thrombectomy and access revision) were 543.2 (95% confidence interval [CI]: 432.9, 673.0) per 1000 person-years in the conventional dialysis group vs. 400.8 (95% CI: 270.2, 572.4) per 1000 person-years in the daily hemodialysis dialysis group (incidence rate ratio = 0.74 with 95% CI: from 0.40 to 1.36, P = 0.33), after adjusting for age, gender, diabetes status, serum phosphorus, hemoglobin level and erythropoietin dose, there was no significant differences in incidence rate of total access procedures (P-value > 0.05). There was no difference in time to first access revision between the daily dialysis and the conventional dialysis groups after adjustment for covariates (hazard ratio = 0.99 95% CI: 0.42, 2.36, P = 0.96). Daily hemodialysis is not associated with increased vascular access complications, or increased vascular access failure rates.
Authors:
Steven G Achinger; T Alp Ikizler; Aihua Bian; Ayumi Shintani; Juan Carlos Ayus
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, N.I.H., Extramural     Date:  2012-09-28
Journal Detail:
Title:  Hemodialysis international. International Symposium on Home Hemodialysis     Volume:  17     ISSN:  1542-4758     ISO Abbreviation:  Hemodial Int     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-04     Completed Date:  2014-02-13     Revised Date:  2014-07-24    
Medline Journal Info:
Nlm Unique ID:  101093910     Medline TA:  Hemodial Int     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  208-15     Citation Subset:  IM    
Copyright Information:
© 2012 The Authors. Hemodialysis International © 2012 International Society for Hemodialysis.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cohort Studies
Female
Humans
Male
Prospective Studies
Renal Dialysis / methods*
Risk Factors
Thrombectomy
Time
Treatment Outcome
Vascular Patency
Young Adult
Grant Support
ID/Acronym/Agency:
U01 DK066481/DK/NIDDK NIH HHS; U01 DK066481/DK/NIDDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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