Document Detail

Long-term effects of clefts on craniofacial morphology in patients with unilateral cleft lip and palate.
MedLine Citation:
PMID:  16241171     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To identify the long-term effects of clefts (intrinsic and functional) on craniofacial growth and to evaluate the possible association between the sizes of the cleft maxillary segment (intrinsic) and alveolar cleft (functional) and the craniofacial morphology in patients with unilateral cleft lip and palate (UCLP). DESIGN: Retrospective case-control study. SETTING: Sri Lankan Cleft Lip and Palate Project. SUBJECTS: Thirty unoperated adult patients with UCLP and 52 normal controls. MAIN OUTCOME MEASURES: Maxillary dental cast was used to measure the sizes of the cleft maxillary segment and alveolar cleft. Cephalometry was used to determine craniofacial morphology. RESULTS: Patients with UCLP had shorter height of the basal maxilla, shorter posterior length of the basal maxilla, and less protruded basal maxilla at the zygomatic level than did control subjects. In patients with UCLP, the posterior height of the basal maxilla was related to the size of the cleft maxillary segment, and there was a tendency toward significant association between the anterior height of the basal maxilla and the size of the alveolar cleft. CONCLUSION: The adverse effects of clefts on the growth of the maxilla in patients with UCLP are restricted to the basal maxilla in size. This growth inhibition is major in height and minor in length. The reduced posterior height of the basal maxilla in unoperated patients with UCLP might be primarily attributed to intrinsic effects, whereas the reduced anterior height of the basal maxilla might be attributed to functional effects.
Yu-Fang Liao; Michael Mars
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association     Volume:  42     ISSN:  1055-6656     ISO Abbreviation:  Cleft Palate Craniofac. J.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-24     Completed Date:  2006-03-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9102566     Medline TA:  Cleft Palate Craniofac J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  601-9     Citation Subset:  D; IM    
Department of Dentistry, Craniofacial Center, Chang Gung Memorial Hospital, Taipei, Taiwan.
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MeSH Terms
Alveolar Process / pathology
Case-Control Studies
Cleft Lip / pathology*,  physiopathology
Cleft Palate / pathology*,  physiopathology
Dental Arch / pathology
Facial Bones / growth & development*
Longitudinal Studies
Mandible / pathology
Maxilla / growth & development,  pathology
Maxillofacial Development / physiology
Retrospective Studies
Skull / growth & development*
Skull Base / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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