| Long-term effects of TRH administration on food intake and body weight in the rat. | |
| | |
MedLine Citation:
|
PMID: 3090567 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effect of long-term TRH administration through drinking water (0.2 mg/ml) on food and water intake and body weight has been studied in three groups of female rats: (1) thyroidectomized, (2) thyroidectomized receiving daily 250 micrograms/kg of L-T4, (3) sham-operated. Treatment with oral TRH for 30 days decreased body weight and increased food intake in sham-operated rats. No TRH effects on body weight or food consumption were observed in either of the other groups of thyroidectomized rats. TRH administration increased circulating T3 levels in sham-operated animals, but had no effects in either hypo- or hyperthyroid, thyroidectomized rats. It can be concluded that the TRH-induced increase on food intake is mediated through the pituitary-thyroid axis. |
| | |
Authors:
|
R Iglesias; M Llobera; E Montoya |
Related Documents
:
|
859727 - Pubertal food intake, body length, weight, and composition in the well fed female rat. 1798777 - The effects of chronic ventromedial hypothalamic stimulation on weight gain in rats. 19744547 - Percent body fat is related to delay and probability discounting for food in humans. 17845247 - Oestradiol, but not genistein, inhibits the rise in food intake following gonadectomy i... 16300427 - Combined dieting and stress evoke exaggerated responses to opioids in binge-eating rats. 17706947 - Dynamic interaction between medial prefrontal cortex and nucleus accumbens as a functio... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Pharmacology, biochemistry, and behavior Volume: 24 ISSN: 0091-3057 ISO Abbreviation: Pharmacol. Biochem. Behav. Publication Date: 1986 Jun |
Date Detail:
|
Created Date: 1986-09-17 Completed Date: 1986-09-17 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0367050 Medline TA: Pharmacol Biochem Behav Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1817-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Body Weight / drug effects* Drinking / drug effects Eating / drug effects* Female Hyperthyroidism / physiopathology Hypothyroidism / physiopathology Rats Rats, Inbred Strains Thyrotropin-Releasing Hormone / pharmacology* Thyroxine / blood Triiodothyronine / blood |
| Chemical | |
Reg. No./Substance:
|
24305-27-9/Thyrotropin-Releasing Hormone; 6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Chronic ethanol administration inhibits calmodulin-dependent Ca++ uptake in synaptosomal membranes.
Next Document: Influence of magnesium on norepinephrine-and histamine-induced contractions of pulmonary vascular sm...