Document Detail

Long-term compliance of salt restriction and blood pressure control status in hypertensive outpatients.
MedLine Citation:
PMID:  20608894     Owner:  NLM     Status:  MEDLINE    
The purpose of the present study was to investigate the long-term compliance with salt restriction and blood pressure (BP) control status in Japanese hypertensive outpatients. Subjects included 103 patients, 59 women and 44 men, mean age 67 +/- 9 years, who underwent successful 24-h home urine collection more than 10 times over an interval of 5 years. Urinary salt, potassium, and creatinine were measured. During the follow-up period (average 8.6 years), participants underwent urine collection 11.4 times in average. Urinary salt excretion at the last visit was significantly lower than that of the first visit (8.2 +/- 3.1 vs. 9.6 +/- 3.7 g/day; p < 0.01). The achievement of urinary salt excretion <6 g/day increased from 18.5% at the first visit to 26.2% at the last visit. Similarly, BP at the last visit was significantly lower than that of the first visit (130 +/- 14/69 +/- 11 vs. 145 +/- 17/86 +/- 12 mmHg; p < 0.01). The achievement rate of BP <140/90 mmHg and <130/85 mmHg also increased significantly during this period (39.2% to 70.8% and 13.7% to 39.6%, respectively, p < 0.01). Results suggest that urinary salt excretion decreased by repeated measurements using 24-h home urine collection. Lifestyle modification including weight loss as well as the intensive antihypertensive treatment contributed to the improved BP control during this period.
Yuko Ohta; Takuya Tsuchihashi; Uran Onaka; Eri Miyata
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental hypertension (New York, N.Y. : 1993)     Volume:  32     ISSN:  1525-6006     ISO Abbreviation:  Clin. Exp. Hypertens.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-10-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9305929     Medline TA:  Clin Exp Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  234-8     Citation Subset:  IM    
Division of Hypertension, Clinical Research Institute, National Kyushu Medical Center, Fukuoka, Japan.
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MeSH Terms
Antihypertensive Agents / therapeutic use
Blood Pressure / drug effects*
Blood Pressure Monitoring, Ambulatory
Creatinine / urine
Diet, Sodium-Restricted*
Hypertension / diagnosis,  diet therapy*,  drug therapy,  urine*
Life Style
Middle Aged
Patient Compliance*
Patient Education as Topic
Potassium / urine
Retrospective Studies
Sodium Chloride / urine
Time Factors
Treatment Outcome
Weight Loss
Reg. No./Substance:
0/Antihypertensive Agents; 60-27-5/Creatinine; 7440-09-7/Potassium; 7647-14-5/Sodium Chloride

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