Document Detail

Long-term cognitive treatment of Alzheimer's disease: a single case study.
MedLine Citation:
PMID:  16509521     Owner:  NLM     Status:  MEDLINE    
The effects of long-term treatment in a demented patient were evaluated in this study. One individual diagnosed with Alzheimer's dementia (AD) was treated with neuropsychological rehabilitation techniques as well as drugs for a period of 2 years and 10 months. An A-B-A-B design was performed for the cognitive treatment. Neuropsychological treatment consisted of a combination of direct re-training and training in activities of daily living. Cognitive performance was monitored with the Mattis Dementia Rating Scale. Results showed improvement and a slower decline during the treatment phases (A) as compared to the no-treatment phases (B). The Conceptualisation and Attention subscales benefited most followed by the Memory subscale. Long-term treatment was shown to be effective in AD. Although cognitive drugs may have been beneficial neuropsychological rehabilitation played an important role in the success of this treatment, appearing as a necessary condition.
Alberto Luis Fernández; Laura M V Manoiloff; Angel A Monti
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuropsychological rehabilitation     Volume:  16     ISSN:  0960-2011     ISO Abbreviation:  Neuropsychol Rehabil     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-03-02     Completed Date:  2006-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9112672     Medline TA:  Neuropsychol Rehabil     Country:  England    
Other Details:
Languages:  eng     Pagination:  96-109     Citation Subset:  IM    
Private Institute of Neurosciences, National University of Córdoba, Argentina.
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MeSH Terms
Activities of Daily Living / psychology
Alzheimer Disease / psychology,  therapy*
Attention / physiology
Cognitive Therapy / methods*
Longitudinal Studies
Memory / physiology
Neuropsychological Tests
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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