Document Detail


Long-term cardiac rhythm and repolarization abnormalities in refractory focal and generalized epilepsy.
MedLine Citation:
PMID:  22709423     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This prospective study evaluated 19 individuals with refractory focal or generalized epilepsy utilizing an implantable cardiac loop recorder. Recording averaged 15 months (range 12-19 months) in 18 patients and 1.5 months in one patient. A median of 37 seizures per patient (range 3-657) occurred, with 1,477 seizures total. Cardiac arrhythmias and repolarization abnormalities occurred frequently (in 42% of patients) in refractory epilepsy, particularly during generalized tonic-clonic and tonic seizures. Patients with Lennox-Gastaut syndrome may be at high risk for cardiac abnormalities.
Authors:
Maromi Nei; Michael R Sperling; Scott Mintzer; Reginald T Ho
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-18
Journal Detail:
Title:  Epilepsia     Volume:  -     ISSN:  1528-1167     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2983306R     Medline TA:  Epilepsia     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Wiley Periodicals, Inc. © 2012 International League Against Epilepsy.
Affiliation:
Departments of Neurology Cardiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, U.S.A.
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