| Long-term betacarotene-supplementation enhances serum insulin concentrations without effect on the onset of puberty in the female goat. | |
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MedLine Citation:
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PMID: 22139337 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The effect of betacarotene (BC) supplementation on the onset of puberty and serum insulin levels in goats was evaluated in the study. In June, prepuberal goats (n=17; 3 months old; 7/8 Saanen-Alpine; 26° NL) were randomly assigned to one of two groups: 1/ betacarotene group supplemented daily with 50 mg of BC (n=9; live weight [LW]: 17.3±1.0 kg; body condition score [BCS]: 3.34±0.12) or 2/ control group (CONT; n=8; LW:16.1±1.0 kg; BCS=3.17±0.12). From June to November, an intermittent blood sampling was performed twice per week in both groups to evaluate serum progesterone (P(4)), while monthly samples were intended for insulin (INS) determination. Initial mean LW (16.7±1.0 kg) and BCS (3.31±0.12) were similar (p>0.05) in both groups. Mean serum insulin (1.37 vs. 1.18±0.09 ng/ml), age of puberty (215.7 vs. 226.5±6.6 days) and the percentage of goats reaching puberty (44.4 vs. 25.0±17.0%) did not differ (p>0.05) between BC and CONT group, respectively. However, increase in serum insulin during the second half of the experiment was observed in BC group (p<0.05) which was positively correlated with LW (r=0.95; p<0.05). In addition, as LW (r=-0.89) and serum insulin (r=-0.76) levels increased, the natural photoperiod decreased, revealing negative correlations (p<0.05) between the respective variables. In this study, BC supplementation did not promote precocious puberty and did not affect the percentage of goats reaching activation of the hypothalamic-hypophyseal-gonadal axis during the establishment of puberty. Nonetheless, BC supplementation positively affected the release pattern of insulin suggesting a potential role of BC as pancreas-activating molecule. |
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Authors:
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Cesar A Meza-Herrera; Luis C Hernández-Valenzuela; Antonio González-Bulnes; Manuel Tena-Sempere; Jose Abad-Zavaleta; Homero Salinas-Gonzalez; Miguel Mellado; Francisco Veliz-Deras |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Reproductive biology Volume: 11 ISSN: 1642-431X ISO Abbreviation: Reprod Biol Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-12-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101160559 Medline TA: Reprod Biol Country: Poland |
Other Details:
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Languages: eng Pagination: 236-49 Citation Subset: IM |
Affiliation:
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Galeana 585 Poniente, Colonia Centro; Lerdo, Durango, 35150 Mexico;e-mail: cmeza2020@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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