| Long-term benefits in lung function and nutritional status of strict metabolic control of cystic fibrosis-related diabetes. | |
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MedLine Citation:
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PMID: 21798655 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Cystic fibrosis related diabetes (CFRD) is a strong determinant for lung function decline and increased mortality. Insulin treatment of CFRD is reportedly beneficial for this situation. We report on the long-term impact of insulin treatment of CFRD on pulmonary function and nutritional status in a CF male patient since diagnosis of diabetes. We report the case of a patient diagnosed with CF at the age of 16. Two years later, he experienced a rapidly evolving decrease in pulmonary function, some months later criteria were met warranting lung transplantation. Concomitantly, he was diagnosed with CFRD and insulin therapy was started. Lung function (spirometry), nutritional status (body mass index) and metabolic control (HbA(1c)) were determined every 3 months. After the introduction of insulin treatment, pulmonary function and nutritional status progressively improved and good glycemic control was achieved. The significant and sustained improvement in pulmonary function allowed for the patient's withdrawal from the lung transplantation program within 4 months, a situation which has been maintained until now, 8 years later. The long follow-up of our patient documents the rapid and prolonged beneficial effect of proper metabolic control of CFRD on the respiratory deterioration in CF. |
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Authors:
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María Martín-Frías; Luis Máiz; Atilano Carcavilla; Raquel Barrio |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-26 |
Journal Detail:
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Title: Archivos de bronconeumologia Volume: - ISSN: 1579-2129 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0354720 Medline TA: Arch Bronconeumol Country: - |
Other Details:
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Languages: ENG; SPA Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2010 SEPAR. Published by Elsevier Espana. All rights reserved. |
Affiliation:
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Unidad de Diabetes Pediátrica, Hospital Ramón y Cajal, Universidad de Alcalá, Madrid, España. |
Vernacular Title:
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Efecto beneficioso y prolongado del buen control metabólico de la diabetes relacionada con fibrosis quística sobre la función pulmonar y el estado nutricional. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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