Document Detail


Long-term anticoagulant therapy after myocardial infarction in women.
MedLine Citation:
PMID:  4174488     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A multicentre trial from five medical departments in Oslo has been carried out to determine the value in women patients of one year's long-term anticoagulant therapy. Follow-up long-term laboratory control and anticoagulant dosage were performed at one centre (the Rikshospitalet). One hundred and fifty-nine patients were assigned randomly into two similar well-matched groups (control and treatment). Dosage was controlled by Thrombotest, aiming at 10-20% levels, and 50% of the tests were less than 14%. Compared with the control group, the treatment group showed a significant reduction in mortality and in reinfarction rate. No serious bleeding complications occurred. It is concluded that women benefit as much as men from long-term anticoagulant therapy.
Authors:
C F Borchgrevink; C Bjerkelund; A M Abrahamsen; G Bay; P Borgen; B Grande; I Helle; H Kjörstad; A M Petersen; T Rörvik; R Thorsen; A Odegaard
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British medical journal     Volume:  3     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1968 Sep 
Date Detail:
Created Date:  1968-10-04     Completed Date:  1968-10-04     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  571-4     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Anticoagulants / adverse effects,  therapeutic use*
Blood Coagulation Tests
Clinical Trials as Topic
Dicumarol / therapeutic use
Female
Follow-Up Studies
Humans
Middle Aged
Myocardial Infarction / drug therapy*,  mortality
Phenindione / therapeutic use
Time Factors
Warfarin / therapeutic use
Chemical
Reg. No./Substance:
0/Anticoagulants; 66-76-2/Dicumarol; 81-81-2/Warfarin; 83-12-5/Phenindione
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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