Document Detail


Long-term Functional and Quality-of-Life Outcomes After IPAA in Children.
MedLine Citation:
PMID:  23303148     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: : The impact of IPAA on long-term outcomes in adults is favorable. Studies on functional outcome and quality of life in children are sparse.
OBJECTIVE: : The aim of this study was to evaluate the functional and quality-of-life outcomes after IPAA in children and to investigate the possible correlations between the two.
DESIGN: : Standardized validated questionnaires of bowel/psychosocial functioning and quality of life were used to assess outcome.
SETTING: : This study was conducted at a tertiary medical center.
PATIENTS: : All children who had surgery at <18 years of age and were followed up at our institute were included. Global Assessment of Function Scale questionnaires were used to evaluate functional outcome. Quality of life in patients >18 years at the time of follow-up was scored by using the Short Form 36 questionnaire completed by the patients. Quality of life in the younger patients at the time of follow-up was scored using the Child Health Questionarie-28 filled by the parents.
RESULTS: : Data were obtained in 26 patients (25 with a preoperative diagnosis of ulcerative colitis) at a median follow-up of 6 years. The median age at surgery was 15 years. Quality of life was comparable to the general population for children >18 at the time of follow-up in 7 of 8 items, but was lower than in the general population in 7 of 12 items for those who were younger at the time of follow-up. The mean functional score was found to be negatively correlated to all 8 Short Form 36 parameters (r > 0.5; p < 0.005), but only to one of the Child Health Questionarie-28 parameters.
LIMITATIONS: : This study was limited by its small sample size.
CONCLUSIONS: : The functional outcomes among pediatric patients undergoing IPAA are good. Parents' perception of their child's quality of life is poorer in comparison with the perception by patients themselves when older and with no correlation to the functional results.
Authors:
Osnat Zmora; Maya Natanson; Iris Dotan; Itzhak Vinograd; Hagith Nagar; Micha Rabau; Hagit Tulchinsky
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diseases of the colon and rectum     Volume:  56     ISSN:  1530-0358     ISO Abbreviation:  Dis. Colon Rectum     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372764     Medline TA:  Dis Colon Rectum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  198-204     Citation Subset:  IM    
Affiliation:
1 Department of Pediatric Surgery, Dana Children's Hospital, Tel-Aviv Sourasky Medical Center, affiliated with the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel 2 Proctology Unit, Department of Surgery, Tel-Aviv University, Tel-Aviv, Israel 3 Comprehensive Pouch Clinic, IBD Center, Department of Gastroenterology and Liver Diseases, Tel-Aviv University, Tel-Aviv, Israel.
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