Document Detail

Long-term ECG in pheochromocytoma.
MedLine Citation:
PMID:  2414009     Owner:  NLM     Status:  MEDLINE    
In 13 patients with pheochromocytoma (in all but 2 cases localization by scintigraphy) investigations using Holter long-term ECG were performed under medication with alpha- and beta-sympathicolytic drugs under bed rest conditions. The incidence of ventricular dysrhythmias hardly exceeded the extent of a normal control group. In 1 case alpha-methyltyrosine caused a first to second degree AV block and beyond this a stable high frequency sinus rate without any adaptation to the environmental requests. In 12 patients the frequency profile showed sudden and inadequate rises of heart rate up to 200% of very short duration, reaching their maximum within about 20 s of the onset of muscular activity. Although less pronounced, these characteristics were still found 1-2 weeks after operation. In our opinion the heart rate profiles described reveal a dysfunction of the entire autonomus nervous system in pheochromocytoma.
H U Bramann; W Zidek; H Vetter
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  72 Suppl 1     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1985  
Date Detail:
Created Date:  1985-11-25     Completed Date:  1985-11-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  163-6     Citation Subset:  IM    
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MeSH Terms
Adrenal Gland Neoplasms / complications*
Arrhythmias, Cardiac / etiology*
Cardiac Complexes, Premature / etiology
Catecholamines / urine
Heart Block / etiology
Heart Rate
Heart Ventricles
Middle Aged
Pheochromocytoma / complications*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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