Document Detail

Long-standing complications after treatment for cancer of the uterine cervix--clinical significance of medical examination at 5 years after treatment.
MedLine Citation:
PMID:  16445648     Owner:  NLM     Status:  MEDLINE    
The purpose of this study is to investigate the side effect in patients who survived for more than 5 years after initial treatment for invasive cervical cancer. Between January 1984 and December 1997, 341 patients underwent primary treatment for invasive cervical cancer. One hundred nine patients who underwent medical examinations at 5 years after primary treatment were reviewed. The patients were divided into three groups: radical surgery alone (group A), radiotherapy alone (group B), and radical surgery with postoperative radiotherapy (group C). Dysuria was seen in 8%, and positive catheterized urine culture was noted in about 20% of groups A and C. Hydronephrosis was seen in 2% and 9% of groups A and B, respectively. Colitis or ulcer detected by proctosigmoidoscopy was noted in 15%, 50%, and 43% of groups A, B, and C, respectively, frequently observed in radiotherapy group (P= 0.0029). Lymphocyst was still present in 6% of group A, and leg edema was noted in 14%, 6%, and 15% of groups A, B, and C, respectively. Long-standing abnormal findings including urinary and bowel complications were presented in this study. Periodic physical examination after treatment should be performed because complications existed over a long time.
Y Matsuura; T Kawagoe; N Toki; M Tanaka; M Kashimura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society     Volume:  16     ISSN:  1048-891X     ISO Abbreviation:  Int. J. Gynecol. Cancer     Publication Date:    2006 Jan-Feb
Date Detail:
Created Date:  2006-01-31     Completed Date:  2006-05-17     Revised Date:  2006-11-07    
Medline Journal Info:
Nlm Unique ID:  9111626     Medline TA:  Int J Gynecol Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  294-7     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Occupational and Environmental Health Japan, Iseigaoka 1-1, Yahata Nisahi-Ku, Kitakyushu, Fukuoka 807-8555, Japan.
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MeSH Terms
Cohort Studies
Combined Modality Therapy / adverse effects
Follow-Up Studies
Hysterectomy / methods
Middle Aged
Monitoring, Physiologic / methods
Neoplasm Invasiveness / pathology*
Neoplasm Recurrence, Local / mortality,  pathology*,  therapy
Neoplasm Staging
Postoperative Complications / epidemiology*
Radiation Injuries / epidemiology*
Radiotherapy, Adjuvant
Retrospective Studies
Survival Rate
Time Factors
Treatment Outcome
Uterine Cervical Neoplasms / mortality,  pathology*,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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