| Long-latency reflex activity in squirrel monkeys with occlusion of the middle cerebral artery. | |
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MedLine Citation:
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PMID: 2441958 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The primate middle cerebral artery (MCA) preparation has been studied as an animal model of human spasticity resulting from stroke. MCA occlusion in 3 squirrel monkeys was accomplished through a transorbital approach and animals were evaluated by 'clinical' examinations and studies of EMG responses to torque motor imposed joint displacement. Animals were transiently hemiparetic but not spastic postoperatively, although all were found to have a large infarct in MCA territory on post-mortem examination. The electromyographic (EMG) response of biceps in normal animals to torque motor imposed elbow extension consisted of both early (M1) and late (M2) components (Tatton et al. 1975). These components were unchanged following MCA occlusion. The EMG response to metacarpophalangeal joint extension in finger flexors or normal animals consisted solely of a long-latency (M2) component (Lenz et al. 1983a). Following MCA occlusion the M2 component in this muscle was decreased or absent, but a short-latency (M1) component appeared. |
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Authors:
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F A Lenz; R R Tasker; W G Tatton; W Halliday |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Electroencephalography and clinical neurophysiology Volume: 67 ISSN: 0013-4694 ISO Abbreviation: Electroencephalogr Clin Neurophysiol Publication Date: 1987 Sep |
Date Detail:
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Created Date: 1987-10-02 Completed Date: 1987-10-02 Revised Date: 2008-09-09 |
Medline Journal Info:
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Nlm Unique ID: 0375035 Medline TA: Electroencephalogr Clin Neurophysiol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 238-46 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain Diseases / physiopathology* Cerebral Arteries* Constriction Disease Models, Animal Electromyography Forelimb / physiopathology Hemiplegia / physiopathology Muscle Spasticity / physiopathology* Reaction Time* Reflex / physiology* Saimiri |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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