Document Detail

Long chain polyunsaturated fatty acids in mothers and term babies.
MedLine Citation:
PMID:  19492914     Owner:  NLM     Status:  MEDLINE    
AIM: To establish the levels of docosahexaenoic acid (DHA) and arachidonic acid (AA) in both plasma and erythrocytes of maternal and cord blood as well as in breast milk of mothers delivering babies at term. METHODS: A total of 148 mothers delivering babies at term were recruited from Bharati Medical Hospital, Pune, India. RESULTS: Levels of DHA and AA in both plasma and erythrocyte were higher in cord blood compared to levels in maternal blood (P<0.001). Maternal plasma and erythrocyte DHA levels had a positive association with the respective levels in cord blood (P<0.001). However, such an association was not seen for AA levels. Maternal plasma omega 3 and omega 6 fatty acids were positively associated with the respective milk fatty acids (P<0.01). CONCLUSIONS: Our results indicate that milk long-chain polyunsaturated fatty acids (LCPUFA) status reflects the concentrations of maternal LCPUFA in women delivering babies at term. Improving the maternal LCPUFA status throughout pregnancy and lactation may improve the milk LCPUFA status and ultimately benefit the infant.
Anitha S Kilari; Savita S Mehendale; Kamini D Dangat; Hemlata R Yadav; Asmita V Kulakarni; Madhavi V Dhobale; Vaishali S Taralekar; Sadhana R Joshi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  37     ISSN:  1619-3997     ISO Abbreviation:  J Perinat Med     Publication Date:  2009  
Date Detail:
Created Date:  2009-09-03     Completed Date:  2010-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  513-8     Citation Subset:  IM    
Department of Nutritional Medicine, Interactive Research School for Health Affairs, Bharati Vidyapeeth University, Pune, India.
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MeSH Terms
Arachidonic Acid / blood,  metabolism
Dietary Fats, Unsaturated / administration & dosage
Docosahexaenoic Acids / blood,  metabolism
Erythrocytes / metabolism
Fatty Acids, Omega-3 / blood,  metabolism
Fatty Acids, Omega-6 / blood,  metabolism
Fatty Acids, Unsaturated / blood*,  metabolism
Fetal Blood / metabolism*
Infant, Newborn
Lactation / metabolism
Milk, Human / metabolism
Nutritional Status
Pregnancy / blood*
Young Adult
Reg. No./Substance:
0/Dietary Fats, Unsaturated; 0/Fatty Acids, Omega-3; 0/Fatty Acids, Omega-6; 0/Fatty Acids, Unsaturated; 25167-62-8/Docosahexaenoic Acids; 506-32-1/Arachidonic Acid

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