Document Detail


Long-chain polyunsaturated fatty acid levels in US donor human milk: meeting the needs of premature infants?
MedLine Citation:
PMID:  22323096     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine fatty acid levels in the US donor milk supply.
STUDY DESIGN: Donor human milk samples from Iowa (n=62), Texas (n=5), North Carolina (n=5) and California (n=5) were analyzed by gas chromatography. Levels in the Iowa donor milk were compared before and after pasteurization using Student's t-test. Docosahexaenoic acid (DHA) and arachidonic acid (ARA) levels were compared among all milk banks using analysis of variance.
RESULT: ARA (0.4 pre, 0.4 post, P=0.18) and DHA (0.073 pre, 0.073 post, P=0.84) were not affected by pasteurization. DHA varied between banks (P<0.0001), whereas ARA did not (P=0.3). DHA levels from all banks were lower than published values for maternal milk and infant formula (P<0.0001).
CONCLUSION: Pasteurization of breastmilk does not affect DHA or ARA levels. However, DHA content in US donor milk varies with bank location and may not meet the recommended provision for preterm infants.
Authors:
M L Baack; A W Norris; J Yao; T Colaizy
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-02-09
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  32     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-30     Completed Date:  2013-05-29     Revised Date:  2014-09-14    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  598-603     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chromatography, Gas
Fatty Acids, Unsaturated / analysis*
Food, Fortified
Humans
Infant Formula / chemistry*
Infant Nutritional Physiological Phenomena
Infant, Newborn
Infant, Premature*
Milk, Human / chemistry*
Pasteurization
Tissue Donors
United States
Grant Support
ID/Acronym/Agency:
K23 HD057232/HD/NICHD NIH HHS; K23 HD057232-02/HD/NICHD NIH HHS; K23 HD057232-03/HD/NICHD NIH HHS; K23HD057232/HD/NICHD NIH HHS; R01 DK081548/DK/NIDDK NIH HHS; R01 DK081548-03/DK/NIDDK NIH HHS; R01DK081548/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Fatty Acids, Unsaturated
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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