Document Detail


Long arm deletion of chromosome 5 in a case of chronic myelomonocytic leukemia.
MedLine Citation:
PMID:  3855687     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The 46,XY,del(5)(q31),del(12)(p11) and 46,X,-Y,del(5)(q31),del(12)(p11), +mar clones were found in the bone marrow cells of a 64-year-old Japanese man with chronic myelomonocytic leukemia (CMML). Although the 5q- anomaly has been reported to occur in various hematologic disorders, a literature survey of CMML cases revealed that the present case is the first instance of CMML with the 5q- anomaly. The possible significance of the chromosome findings is discussed.
Authors:
Y Sato; K Kubota; K Suda; A Tsuboyama; S Sakamoto; Y Miura
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  15     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-04-11     Completed Date:  1985-04-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  269-75     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Bone Marrow / pathology
Chromosome Aberrations / pathology
Chromosome Deletion
Chromosome Disorders
Chromosomes, Human, 4-5*
Humans
Karyotyping
Leukemia, Myeloid / genetics*
Male
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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