Document Detail


Long-alkyl-chain quaternary ammonium lactate based ionic liquids.
MedLine Citation:
PMID:  18729115     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new group of quaternary ammonium lactate based ionic liquids have been prepared and characterized. Didecyldimethylammonium (DDA) and benzalkonium (BA) D,L- and L-lactates are air-stable, hydrophilic, surface-active salts. They are very effective antibacterial and antifungal agents, especially the DDA lactates, against Streptococcus mutants and Candida albicans. Their activities are comparable or more effective than the original benzalkonium chloride. In addition, they have been shown to be good insect-feeding deterrents. However, they are poor antifungal agents for wood preservation. The toxicity of the DDA and BA lactates has also been studied and the results are presented in this paper.
Authors:
Jacek Cybulski; Anna Wiśniewska; Anna Kulig-Adamiak; Lidia Lewicka; Anna Cieniecka-Rosłonkiewicz; Kazimierz Kita; Andrzej Fojutowski; Jan Nawrot; Katarzyna Materna; Juliusz Pernak
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chemistry (Weinheim an der Bergstrasse, Germany)     Volume:  14     ISSN:  0947-6539     ISO Abbreviation:  Chemistry     Publication Date:  2008  
Date Detail:
Created Date:  2008-10-16     Completed Date:  2008-12-10     Revised Date:  2009-08-04    
Medline Journal Info:
Nlm Unique ID:  9513783     Medline TA:  Chemistry     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  9305-11     Citation Subset:  IM    
Affiliation:
Industrial Chemistry Research Institute ul. Rydygiera 8, 01-793 Warsaw, Poland.
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MeSH Terms
Descriptor/Qualifier:
Alkanes / chemistry*
Animals
Bacteria / drug effects
Feeding Behavior / drug effects
Female
Fungi / drug effects
Insects / physiology
Ionic Liquids / chemistry*,  pharmacology,  toxicity
Lactic Acid / chemical synthesis*,  chemistry,  pharmacology*,  toxicity
Lethal Dose 50
Quaternary Ammonium Compounds / chemistry*
Rats
Surface Properties
Wood / drug effects
Chemical
Reg. No./Substance:
0/Alkanes; 0/Ionic Liquids; 0/Quaternary Ammonium Compounds; 50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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