Document Detail


Long-Term Sequelae of Childhood Bacterial Meningitis.
MedLine Citation:
PMID:  23539430     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In most high-income countries, fewer children now acquire meningitis, and many of those who do will survive. Globally, however, meningitis still remains a significant cause of child morbidity and mortality. In this article, the authors review recent evidence on the morbidity faced by childhood survivors of bacterial meningitis. Outcomes vary by bacterial pathogen, with around a 20 % risk for severe sequelae (most commonly, neurocognitive) by all pathogenic causes. Pneumococcal, tuberculosis, and group B streptococcal meningitis lead to the highest rates of sequelae. Recent epidemiological shifts in the major pathogens causing meningitis, as well as varied regional settings between studies, limit generalizability of evidence in the literature, and better research using longitudinal data and case-control methodology is required, especially in low-income countries. However, the consistently high levels of complications described in the literature call for more widespread vaccination programs for prevention and a greater focus on potential complications by educators and health-care providers to support childhood survivors of bacterial meningitis and their families.
Authors:
Lee D Hudson; Russell M Viner; Deborah Christie
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-3-29
Journal Detail:
Title:  Current infectious disease reports     Volume:  -     ISSN:  1523-3847     ISO Abbreviation:  Curr Infect Dis Rep     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-3-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888983     Medline TA:  Curr Infect Dis Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
University College London Hospital, London, UK, l.hudson@ucl.ac.uk.
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