| Long-Term Management of Esophageal Varices by Endoscopic Sclerotherapy (EST): A Review of 12 Years' Experience. | |
| | |
| Jump to Full Text | |
MedLine Citation:
|
PMID: 18493407 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
A total of 566 patients with variceal bleeding caused by cirrhosis of the liver, noncirrhotic portal fibrosis (NCPF) and extrahepatic portal venous obstruction (EHO) were treated by repeated endoscopic injection sclerotherapy. This decreased rebleeding was evidenced by a reduction in mean bleeding risk factor and transfusion requirement. Both the factors were significantly (P < 0.001) decreased in all three groups of patients. Rebleeding occurred before eradication in 27.7% of patients with cirrhosis, 24.3% of those with NCPF, and 11% of those with EHO. Significantly more patients with cirrhosis and NCPF bled in comparison to EHO. Irrespective of the etiology, fewer patients of Child's A class bled than those of Child's B and C classes (P < 0.001). The median bleeding-free period was longer in patients with EHO than in those with cirrhosis (P < 0.05). This period was also significantly longer in Child's A class than in Child's B and the latter had a longer median bleeding-free period than Child's C class (P < 0.01). Variceal eradication was achieved in 80% of patients with cirrhosis, 87% of patients with NCPF, and 90% of patients with EHO. The success of variceal eradication was higher in EHO patients in contrast with patients with cirrhosis of the liver. Similarly, eradication was better in Child's A class patients than in Child's B and C class patients. Recurrence of varices and complications were not influenced by the Child's status or etiology of portal hypertension. The probability of survival at 10 years was higher in patients with EHO (88%) and NCPF (80%) than in patients with cirrhosis (50%). Similarly, patients with Child's A (88%) status survived longer than those with Child's B (42%) status, and patients with Child's B status had a longer survival than Child's C status patients (0%). Thus, endoscopic variceal sclerotherapy appears to be a useful procedure for the long-term management of patients after an esophageal variceal bleeding irrespective of the etiology of portal hypertension. |
| | |
Authors:
|
D K Bhargava; S Dasarathy; S Saksena |
Related Documents
:
|
7793487 - A prospective multicenter evaluation of preoperative hemostatic screening tests. the fr... 535127 - Phase-ii trial of tamoxifen in advanced breat cancer. 16935367 - Arteriotomy closure device application following percutaneous coronary intervention may... 15311167 - Literacy and numeracy skills and anticoagulation control. 6824147 - The scrotal mass: cause and diagnosis. 9476847 - Small airways function in patients with inflammatory bowel disease. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Diagnostic and therapeutic endoscopy Volume: 2 ISSN: 1070-3608 ISO Abbreviation: Diagn Ther Endosc Publication Date: 1996 |
Date Detail:
|
Created Date: 2008-05-21 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9502019 Medline TA: Diagn Ther Endosc Country: United States |
Other Details:
|
Languages: eng Pagination: 211-7 Citation Subset: - |
Affiliation:
|
Department of Gastroenterology All India Institute of Medical Sciences New Delhi 110029 India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
|
Journal Information Journal ID (nlm-ta): Diagn Ther Endosc ISSN: 1070-3608 ISSN: 1029-0516 Publisher: Hindawi Publishing Corporation |
Article Information Download PDF  Copyright ? 1996 Hindawi Publishing Corporation. open-access: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Received Day: 5 Month: 6 Year: 1995 Accepted Day: 13 Month: 11 Year: 1995 Print publication date: Year: 1996 Volume: 2 Issue: 4 First Page: 211 Last Page: 217 ID: 2362538 PubMed Id: 18493407 Publisher Item Identifier: S1070360896000161 DOI: 10.1155/DTE.2.211 |
| Long-Term Management of Esophageal Varices by Endoscopic Sclerotherapy (EST): A Review of 12 Years' Experience | |
| Dinesh K. Bhargava | |
| S. Dasarathy | |
| Sushma Saksena | |
|
1Department of GastroenterologyAll India Institute of Medical SciencesNew Delhi110029India |
|
Article Categories:
|
|
Previous Document: Endobronchial electrocautery using snare.
Next Document: Endoscopic evaluation of peptic ulcer disease during ramadan fasting.