Document Detail

Long-term follow-up after transvenous single coil embolization of patent ductus arteriosus in dogs.
MedLine Citation:
PMID:  21039864     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Long-term follow-up studies after interventional therapy of patent ductus arteriosus (PDA) in dogs are rare.
HYPOTHESIS: Transvenous PDA embolization with a single detachable coil is a highly effective method in patients with an angiographically determined PDA≤4.0 mm.
ANIMALS: Twenty-eight dogs with an angiographic PDA≤4.0 mm were included.
METHODS: Prospective follow-up study after PDA coil embolization.
RESULTS: The median follow-up time was 792 days (range, 2-3, 248 days). The rate of complete closure demonstrated by Doppler color flow was 54% at day 3 after intervention and the final cumulative rate was 71%. The rate of complete closure was significantly different between small and moderately sized PDA over the study period (P<.0001) and finally was 100 and 50%, respectively. In 16 dogs with complete closure, no recanalization was found. Disappearance of the continuous heart murmur was found in 89% after 3 days, and this increased to a final cumulative rate of 96%. Indexed left ventricular internal diameter in diastole (LVDd-I) decreased significantly (P<.0001). In the group with moderately sized PDA, a significant difference (P=.0256) was seen in LVDd-I between patients with and without residual shunt after exclusion of patients with persistent severe mitral valve regurgitation.
CONCLUSION AND CLINICAL IMPORTANCE: Long-term follow-up after single coil embolization showed complete closure in all small PDA but a residual shunt with mild hemodynamic consequences was present in half of the moderately sized PDA.
N Hildebrandt; C Schneider; T Schweigl; M Schneider
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Publication Detail:
Type:  Journal Article     Date:  2010-10-12
Journal Detail:
Title:  Journal of veterinary internal medicine / American College of Veterinary Internal Medicine     Volume:  24     ISSN:  0891-6640     ISO Abbreviation:  J. Vet. Intern. Med.     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2010-11-08     Completed Date:  2011-02-11     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  8708660     Medline TA:  J Vet Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1400-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 by the American College of Veterinary Internal Medicine.
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MeSH Terms
Dog Diseases / surgery*
Ductus Arteriosus, Patent / surgery,  veterinary*
Embolization, Therapeutic / veterinary*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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