| Long-term follow-up after transvenous single coil embolization of patent ductus arteriosus in dogs. | |
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MedLine Citation:
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PMID: 21039864 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Long-term follow-up studies after interventional therapy of patent ductus arteriosus (PDA) in dogs are rare. Hypothesis: Transvenous PDA embolization with a single detachable coil is a highly effective method in patients with an angiographically determined PDA≤4.0 mm. ANIMALS: Twenty-eight dogs with an angiographic PDA≤4.0 mm were included. METHODS: Prospective follow-up study after PDA coil embolization. RESULTS: The median follow-up time was 792 days (range, 2-3, 248 days). The rate of complete closure demonstrated by Doppler color flow was 54% at day 3 after intervention and the final cumulative rate was 71%. The rate of complete closure was significantly different between small and moderately sized PDA over the study period (P<.0001) and finally was 100 and 50%, respectively. In 16 dogs with complete closure, no recanalization was found. Disappearance of the continuous heart murmur was found in 89% after 3 days, and this increased to a final cumulative rate of 96%. Indexed left ventricular internal diameter in diastole (LVDd-I) decreased significantly (P<.0001). In the group with moderately sized PDA, a significant difference (P=.0256) was seen in LVDd-I between patients with and without residual shunt after exclusion of patients with persistent severe mitral valve regurgitation. CONCLUSION AND CLINICAL IMPORTANCE: Long-term follow-up after single coil embolization showed complete closure in all small PDA but a residual shunt with mild hemodynamic consequences was present in half of the moderately sized PDA. |
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Authors:
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N Hildebrandt; C Schneider; T Schweigl; M Schneider |
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Publication Detail:
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Type: Journal Article Date: 2010-10-12 |
Journal Detail:
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Title: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine Volume: 24 ISSN: 0891-6640 ISO Abbreviation: J. Vet. Intern. Med. Publication Date: 2010 Nov-Dec |
Date Detail:
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Created Date: 2010-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8708660 Medline TA: J Vet Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 1400-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 by the American College of Veterinary Internal Medicine. |
Affiliation:
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Small Animal Clinic, Internal Medicine, Justus-Liebig-University Giessen, Giessen, Hessen, Germany. nicolai.hildebrandt@vetmed.uni-giessen.de |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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