| Long Term Follow-Up of Early Mycosis Fungoides Patients treated with Narrowband Ultraviolet B Phototherapy. | |
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MedLine Citation:
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PMID: 23030414 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Background: Narrowband ultraviolet B (UVB) provides complete response (CR) in 54 to 91% of early mycosis fungoides (MF) patients. Data concerning relapse rate and relapse-free interval after discontinuation of therapy need clarification. The purpose of this study was to evaluate the relapse rate and the relapse-free intervals of early MF patients after achieving complete response with narrowband UVB phototherapy. Methods: Retrospective evaluation of data, which belong to early MF patients treated with narrowband UVB phototherapy between May 2000 and July 2010, and followed-up until May 2012 in a single institution, for the occurrence of relapse and the time to relapse. Results: Of 31 patients, who were followed-up for a mean of 56.5±30.2 months, (median 55 months, range 20-120 months). Relapse was observed in 11 (35.5%) of these patients, within a mean of 28.8 ± 18.2 months (median, 33 months, range, 4-59 months), whereas 20 (64.5%) patients stayed relapse-free for a mean of 54.2 ± 28.8 months (median, 55.5 months, range, 20 -119 months). Patients received maintenance phototherapy with a median duration of 12 months (range 1-30 months) after achieving complete response. Conclusion: Results indicate that narrowband UVB phototherapy may induce low relapse rates and long relapse-free intervals for early MF. |
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Authors:
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Gonca Elcin; Nilay Duman; Sevilay Karahan; Sibel Ersoy-Evans; Gul Erkin; Aysen Karaduman; Asli Hapa; Nilgün Atakan; Tulin Akan; Sedef Sahin |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-3 |
Journal Detail:
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Title: The Journal of dermatological treatment Volume: - ISSN: 1471-1753 ISO Abbreviation: J Dermatolog Treat Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8918133 Medline TA: J Dermatolog Treat Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Hacettepe University Faculty of Medicine Department of Biostatistics , Ankara , Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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