| Long-term clinical outcome after percutaneous coronary intervention in grafts vs native vessels in patients with previous coronary artery bypass grafting. | |
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MedLine Citation:
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PMID: 22019279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The long-term clinical outcome of patients with previous coronary artery bypass grafting (CABG), undergoing percutaneous coronary intervention (PCI) is not clear. METHODS: Observational, retrospective study of post-CABG patients, who underwent PCI in either a graft or a native vessel. RESULTS: Out of 221 consecutive patients, those with PCI in both native vessel and graft (N=16) and missing follow-up data (N=15) were excluded. Out of the remaining 190 patients (age 67.9±9.6 years; 90.0% men), the graft-PCI group (N=88) had more occluded native vessels (2.1±0.8 vs 1.6±0.8; P<0.001), and fewer totally occluded grafts (0.55±0.6 vs 0.75±0.8; P=0.05) compared with the native vessel-PCI group (N=102). On follow-up (median duration 28 months), the incidence of major adverse cardiac events (MACEs), cardiac death, and repeat revascularization was higher in graft-PCI group compared with native vessel-PCI group (43.2% vs 19.6%, log-rank P<0.001; 19.3% vs 6.9%, log-rank P=0.008; and 23.9% vs 12.7%, log-rank P=0.02, respectively). Graft-PCI was independently associated with higher risk for major adverse cardiac events (hazard ratio [HR], 2.84; 95% confidence interval [CI], 1.45-5.57; P=0.002), cardiac death (HR, 3.44; 95% CI, 1.16-10.22; P=0.03) and repeat revascularization (HR, 2.41; 95% CI, 1.02-5.72; P=0.046). CONCLUSIONS: Post-CABG patients, undergoing graft compared with native vessel-PCI, have worse long-term clinical outcome. Prospective studies are needed to elucidate the optimal revascularization strategy for such patients. |
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Authors:
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Ioanna Xanthopoulou; Periklis Davlouros; Grigorios Tsigkas; Aggeliki Panagiotou; Georgios Hahalis; Dimitrios Alexopoulos |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2011-10-22 |
Journal Detail:
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Title: The Canadian journal of cardiology Volume: 27 ISSN: 1916-7075 ISO Abbreviation: Can J Cardiol Publication Date: 2011 Nov-Dec |
Date Detail:
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Created Date: 2011-11-28 Completed Date: 2012-01-19 Revised Date: 2012-02-28 |
Medline Journal Info:
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Nlm Unique ID: 8510280 Medline TA: Can J Cardiol Country: England |
Other Details:
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Languages: eng Pagination: 716-24 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Patras University Hospital, Cardiology Department, Patras, Greece. jxanthop@yahoo.gr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Balloon, Coronary / methods* Coronary Artery Bypass* Coronary Restenosis / epidemiology, etiology, therapy* Coronary Stenosis / surgery* Electrocardiography Female Follow-Up Studies Graft Occlusion, Vascular / complications, epidemiology, therapy* Humans Incidence Male Prognosis Retrospective Studies Survival Rate / trends Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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