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Long Term Clinical Consequences Of Urinary Tract Infections During Childhood: A Review.
MedLine Citation:
PMID:  22784016     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Kidney scarring related to urinary tract infection in childhood has been considered the cause of serious long term clinical consequences. This assumption is now debated, as the advent of routine antenatal ultrasound in the 80s has shown that a consistent part of the changes previously attributed to post-infectious scarring is mainly due to congenital malformations. With the aim of determining what is presently known on the long term clinical consequences of UTIs in childhood, we performed a review of the literature on the relation between UTIs and blood pressure, renal function, growth and pregnancy-related complications. By searching Medline/PubMed and Embase from 1980 to 2011 we identified 20 cohorts of children from 23 papers. Conclusions:  Renal function: there are no clear data to establish long-term consequences following UTIs during childhood. Most data seem to show that the outcome of renal function can already be delineated at first presentation or in the initial years of follow-up; only 0.4% of children with normal renal function at start presented a decrease during follow-up. Hypertension: there is a low risk, associated with renal damage. Growth and pregnancy related complications: the few available data seem to exclude a major influence of UTIs. © 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
Authors:
Antonella Toffolo; Anita Ammenti; Giovanni Montini
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-11
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
Affiliation:
Pediatric Unit, Hospital of Oderzo, Oderzo, Italy Gemini Medicina Specialistica, Parma, Italy Nephrology, Dialysis Unit, Department of Pediatrics, Azienda Ospedaliera Universitaria, Sant'Orsola-Malpighi, Bologna, Italy.
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