| Long-Term Changes in Left Ventricular Function Following Intracoronary Stem Cell Transplantation for Acute Myocardial Infarction. | |
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MedLine Citation:
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PMID: 21411206 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Controversy surrounds the long-term effects of intracoronary bone marrow stem cell transplantation after ST-elevation acute myocardial infarction (STEAMI). We report on the long-term changes in left ventricular function observed in 29 patients with STEAMI who were treated using this technique. Cardiac magnetic resonance imaging was performed at baseline, 6 months after transplantation, and long-term follow-up (median 27 months, interquartile range 24-35 months). The left ventricular ejection fraction had improved significantly by 6 months (from 47.6±8.9% to 52.7±11.6%; P=.001) and this improvement was maintained long-term, at 52.4±11.8% (P=.01 vs. baseline and P=.999 vs. 6 months). There was no significant change from baseline in end-diastolic or end-systolic ventricular volume. Our findings indicate the improvement in injection fraction occurs soon after stem cell transplantation, within the first 6 months, and remains unchanged at long-term follow-up. Full English text available from: www.revespcardiol.org. |
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Authors:
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Ana Revilla; Javier López; Roman Arnold; Pedro Luis Sánchez; Adolfo Villa; Marta Pinedo; Francisco Fernández-Avilés; José Alberto San Román |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-14 |
Journal Detail:
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Title: Revista espanola de cardiologia Volume: - ISSN: 1579-2242 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404277 Medline TA: Rev Esp Cardiol Country: - |
Other Details:
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Languages: ENG; SPA Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2010 Sociedad Española de Cardiología. Published by Elsevier Espana. All rights reserved. |
Affiliation:
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Unidad de Imagen Cardiaca (ICICORELAB), Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico Universitario, Valladolid, España. |
Vernacular Title:
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Evolución a largo plazo de la función ventricular tras la terapia celular intracoronaria en el infarto agudo de miocardio. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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