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Locust bean gum: Exploring its potential for biopharmaceutical applications.
MedLine Citation:
PMID:  22923958     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Polysaccharides have been finding, in the last decades, very interesting and useful applications in the biomedical and, specifically, in the biopharmaceutical field. Locust bean gum is a polysaccharide belonging to the group of galactomannans, being extracted from the seeds of the carob tree (Ceratonia siliqua). This polymer displays a number of appealing characteristics for biopharmaceutical applications, among which its high gelling capacity should be highlighted. In this review, we describe critical aspects of locust bean gum, contributing for its role in biopharmaceutical applications. Physicochemical properties, as well as strong and effective synergies with other biomaterials are described. The potential for in vivo biodegradation is explored and the specific biopharmaceutical applications are discussed.
Authors:
Marita Dionísio; Ana Grenha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pharmacy & bioallied sciences     Volume:  4     ISSN:  0975-7406     ISO Abbreviation:  J Pharm Bioallied Sci     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-08-27     Completed Date:  2012-10-02     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101537209     Medline TA:  J Pharm Bioallied Sci     Country:  India    
Other Details:
Languages:  eng     Pagination:  175-85     Citation Subset:  -    
Affiliation:
CBME - Centre for Molecular and Structural Biomedicine/IBB - Institute for Biotechnology and Bioengineering, Faculty of Sciences and Technology, University of Algarve, Campus de Gambelas, Faro, Portugal.
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