Document Detail


Locust adipokinetic hormone stimulates lipid mobilization in Manduca sexta.
MedLine Citation:
PMID:  6626231     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Adipokinetic hormone, a decapeptide isolated from the locust, stimulates mobilization of diacylglycerols from the locust fat body and loading of the lipid transport protein, lipophorin. Injection of the synthetic locust adipokinetic hormone into a sphinx moth, Manduca sexta, causes lipid loading of lipophorin. The lipophorin decreases in density from 1.11 to 1.06 g/ml, and a soluble protein from the hemolymph (apolipophorin III) associates with the lipophorin particle. Administration of intermediate doses of hormone indicates that lipophorin is converted directly to the low density form; no appreciable amounts of intermediate density particles are formed.
Authors:
J P Shapiro; J H Law
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Biochemical and biophysical research communications     Volume:  115     ISSN:  0006-291X     ISO Abbreviation:  Biochem. Biophys. Res. Commun.     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372516     Medline TA:  Biochem Biophys Res Commun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  924-31     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / metabolism
Animals
Carrier Proteins / metabolism
Diglycerides / metabolism
Grasshoppers
Hemolymph / analysis
Insect Hormones / isolation & purification,  pharmacology*
Insects / metabolism
Lepidoptera / metabolism*
Lipid Mobilization / drug effects*
Lipoproteins*
Male
Molecular Weight
Moths / metabolism*
Grant Support
ID/Acronym/Agency:
GM 29238/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Carrier Proteins; 0/Diglycerides; 0/Insect Hormones; 0/Lipoproteins; 0/lipophorin; 53027-55-7/adipokinetic hormone (locust)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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