Document Detail


Locomotor activity but not conditioned place preference is differentially affected by a moderate dose of ethanol administered to P and NP rats.
MedLine Citation:
PMID:  1605883     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The conditioned place preference (CPP) test and spontaneous motor activity were used in order to determine if ethanol-preferring (P) rats differ from ethanol nonpreferring (NP) rats after the administration of a moderate (1.0 g/kg) dose of ethanol. Results indicate that both of the selectively bred lines of rats found ethanol aversive, with little difference between the P and the NP rats. In contrast, the NP rats were shown to be more sensitive to the motor-impairing effect of ethanol.
Authors:
M D Schechter
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Alcohol (Fayetteville, N.Y.)     Volume:  9     ISSN:  0741-8329     ISO Abbreviation:  Alcohol     Publication Date:    1992 May-Jun
Date Detail:
Created Date:  1992-07-23     Completed Date:  1992-07-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8502311     Medline TA:  Alcohol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  185-8     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Northeastern Ohio Universities College of Medicine, Rootstown 44272.
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking*
Animals
Dose-Response Relationship, Drug
Environment*
Ethanol / pharmacology*
Male
Motor Activity / drug effects*
Rats
Rats, Mutant Strains
Reinforcement (Psychology)
Grant Support
ID/Acronym/Agency:
8598//PHS HHS
Chemical
Reg. No./Substance:
64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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