Document Detail

Locomotor activity but not conditioned place preference is differentially affected by a moderate dose of ethanol administered to P and NP rats.
MedLine Citation:
PMID:  1605883     Owner:  NLM     Status:  MEDLINE    
The conditioned place preference (CPP) test and spontaneous motor activity were used in order to determine if ethanol-preferring (P) rats differ from ethanol nonpreferring (NP) rats after the administration of a moderate (1.0 g/kg) dose of ethanol. Results indicate that both of the selectively bred lines of rats found ethanol aversive, with little difference between the P and the NP rats. In contrast, the NP rats were shown to be more sensitive to the motor-impairing effect of ethanol.
M D Schechter
Related Documents :
2621473 - Effect of prenatal exposure to ethanol on the ultrastructure of layer v of mature rat s...
11002903 - The microstructure of ethanol drinking: genetic and behavioral factors in the control o...
9042583 - Nociceptin/orphanin fq microinjected into hippocampus impairs spatial learning in rats.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Alcohol (Fayetteville, N.Y.)     Volume:  9     ISSN:  0741-8329     ISO Abbreviation:  Alcohol     Publication Date:    1992 May-Jun
Date Detail:
Created Date:  1992-07-23     Completed Date:  1992-07-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8502311     Medline TA:  Alcohol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  185-8     Citation Subset:  IM    
Department of Pharmacology, Northeastern Ohio Universities College of Medicine, Rootstown 44272.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Alcohol Drinking*
Dose-Response Relationship, Drug
Ethanol / pharmacology*
Motor Activity / drug effects*
Rats, Mutant Strains
Reinforcement (Psychology)
Grant Support
8598//PHS HHS
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Alcohol reduces the number of pheochromocytoma (PC12) cells in culture.
Next Document:  Breath acetaldehyde following ethanol consumption.