Document Detail


Locked-in syndrome: A rare manifestation of pediatric stroke.
MedLine Citation:
PMID:  19907940     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Locked-in syndrome is characterized by upper motor neuron quadriplegia, paralysis of lower cranial nerves, bilateral horizontal gaze palsy and anarthria, with preserved consciousness. It is due to a ventral pontine lesion following a basilar artery occlusion. We report the first Indian case report of locked-in syndrome, a 10-year old girl in whom the syndome was preceded by a 'herald hemiparesis'. Although the exact etiology for the basilar artery occlusion could not be determined, treatment with low molecular weight heparin and warfarin was followed by partial recovery.
Authors:
Monica Juneja; Rahul Jain; Swati Singhal; Devendra Mishra; Sapna Singh
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-11-12
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  76     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-11-12     Completed Date:  2010-02-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  1053-5     Citation Subset:  IM    
Affiliation:
Department of Pediatric, Maulana Azad Medical College and Associated Lok Nayak Hospital, Bahadur Shah Zafar Marg, New Delhi, India.
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MeSH Terms
Descriptor/Qualifier:
Arterial Occlusive Diseases / complications,  diagnosis*,  drug therapy
Basilar Artery / pathology*
Child
Female
Follow-Up Studies
Heparin, Low-Molecular-Weight / therapeutic use
Humans
India
Magnetic Resonance Angiography
Neuropsychological Tests
Quadriplegia / diagnosis,  drug therapy,  etiology*
Rare Diseases
Recovery of Function
Severity of Illness Index
Stroke / complications,  diagnosis*,  drug therapy
Treatment Outcome
Warfarin / therapeutic use
Chemical
Reg. No./Substance:
0/Heparin, Low-Molecular-Weight; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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