| Location of proliferating gingival cells following toothbrushing stimulation. | |
| | |
MedLine Citation:
|
PMID: 17241434 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: Mechanical stimulation by toothbrushing promotes healing of gingivitis through accelerating cell proliferation. Junctional epithelium proliferates at periodontal pocket formation. A question is arisen whether toothbrushing contributes to the repair of gingival inflammation or deterioration of pocket formation. The location of proliferating cells in gingiva stimulated mechanically by toothbrushing was investigated. MATERIALS AND METHODS: A total of 24 teeth of dogs underwent daily plaque removal with a curette (plaque removal) or both plaque removal and toothbrushing (toothbrushing). Proliferative activity of gingival cells in six individual zones was evaluated by assaying expression of proliferating cell nuclear antigen (PCNA). RESULTS: Toothbrushing increased densities of PCNA-positive basal cells in the junctional epithelium, connective tissues adjacent to the junctional epithelium, the alveolar bone of the oral epithelial side and the oral epithelium. However, the densities of PCNA-positive cells at the apical portion of the junctional epithelium, connective tissues adjacent to the cementum and the alveolar bone of the periodontal ligament side did not increase following toothbrushing. CONCLUSIONS: Toothbrushing promotes proliferation of gingival cells other than fibroblasts in periodontium and basal cells in the apical portion of the junctional epithelium. The repair of periodontal tissues might be promoted by toothbrushing within the limit of the direct mechanical stimulation. |
| | |
Authors:
|
T Tomofuji; T Sakamoto; D Ekuni; T Yamamoto; T Watanabe |
Related Documents
:
|
21364414 - Optimization of human tendon tissue engineering: peracetic acid oxidation for enhanced ... 1697604 - Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells. 19602254 - Differences in regulation of tight junctions and cell morphology between vhl mutations ... 1426144 - Intercellular communication in smooth muscle. 15956554 - Extensive syncytium formation mediated by the reovirus fast proteins triggers apoptosis... 6661704 - Effects of nacl on the uptake of alpha-[14c]aminoisobutyric acid by the halotolerant ba... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Oral diseases Volume: 13 ISSN: 1354-523X ISO Abbreviation: Oral Dis Publication Date: 2007 Jan |
Date Detail:
|
Created Date: 2007-01-23 Completed Date: 2007-03-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9508565 Medline TA: Oral Dis Country: Denmark |
Other Details:
|
Languages: eng Pagination: 77-81 Citation Subset: D |
Affiliation:
|
Department of Oral Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alveolar Process
/
cytology Animals Cell Count Cell Proliferation Connective Tissue Cells / physiology Curettage / instrumentation Dental Cementum / cytology Dental Plaque / therapy Dental Scaling / instrumentation Dogs Epithelial Attachment / cytology Epithelial Cells / physiology Fibroblasts / cytology Gingiva / cytology* Physical Stimulation Proliferating Cell Nuclear Antigen / analysis Toothbrushing* |
| Chemical | |
Reg. No./Substance:
|
0/Proliferating Cell Nuclear Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Association of lip pigmentation with smoking and gingival melanin pigmentation.
Next Document: Clinicopathological analysis of osteosarcoma of jaw bones.