Document Detail


Location of parathyroid adenomas: 7-year experience.
MedLine Citation:
PMID:  20828518     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the most common location of parathyroid adenomas.
METHODS: Data from 147 patients who underwent parathyroidectomy for primary hyperparathyroidism in Montreal at a McGill University teaching hospital between January 2001 and January 2008 were reviewed retrospectively. Patients with histopathologic confirmation of parathyroid hyperplasia were excluded from the study (n = 26). The 121 patients with confirmed adenomas were grouped according to the locations of the tumour into right superior, right inferior, left superior, left inferior, and ectopic.
RESULTS: The left inferior parathyroid glands were the most common site of adenomas. This was the case for 50 patients (41.32% [mean 0.41; 95% CI 0.324-0.506]). The right inferior parathyroid glands were the site in 40 patients (33.06% [mean 0.33; 95% CI 0.248-0.422]). The remainder of the adenomas were distributed as follows: the left superior in 19 patients (15.7% [mean 0.157; 95% CI 0.097-0.234]), the right superior in 10 patients (8.26% [mean 0.0826; 95% CI 0.040-0.147]), and the ectopic in 2 patients (1.65% [mean 0.0165; 95% CI 0.002-0.058]).
CONCLUSIONS: In this study, the most common site of adenoma was the left inferior parathyroid gland. This information provides parathyroid surgeons with a starting point when imaging fails to localize the site of the adenoma, which allows for the possibility of minimally invasive surgery especially if used in conjunction with intraoperative parathyroid hormone.
Authors:
Hani Z Marzouki; Mallory Chavannes; Michael Tamilia; Michael P Hier; Martin J Black; Mark Levental; Richard J Payne
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale     Volume:  39     ISSN:  1916-0216     ISO Abbreviation:  J Otolaryngol Head Neck Surg     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-10     Completed Date:  2011-02-01     Revised Date:  2013-04-10    
Medline Journal Info:
Nlm Unique ID:  101479544     Medline TA:  J Otolaryngol Head Neck Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  551-4     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Jewish General Hospital, 3755 Chemin de la Cote-Ste-Catherine Road, Montreal, QC H3T 1E2.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Diagnosis, Differential
Female
Follow-Up Studies
Humans
Hyperparathyroidism, Primary / diagnosis,  surgery*
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Parathyroid Neoplasms / diagnosis*,  surgery
Parathyroidectomy
Reproducibility of Results
Retrospective Studies
Time Factors
Tomography, X-Ray Computed / methods*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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