Document Detail

Locally made ready to use therapeutic food for treatment of malnutrition a randomized controlled trial.
MedLine Citation:
PMID:  20972285     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the effectiveness of a locally made ready-to-use therapeutic food (RUTF) in decreasing mild to moderate malnutrition.
DESIGN: A randomized open label, controlled trial.
SETTING: Pre-schools run by the Department of Community Health in Kaniyambadi administrative block, Vellore, India; duration of follow-up 3 months from the date of recruitment.
PARTICIPANTS: Pupils aged 18 -60 months with Weight-for-Age 2 SD.
INTERVENTIONS: A locally produced energy-dense supplement (RUTF), and the current standard of care [teaching caregivers how to make a fortified cereal-milk supplement called High Calorie Cereal Milk (HCCM)].
MAIN OUTCOME MEASURES: Increase in weight-for-age status; increase in levels of plasma zinc, vitamin B12, serum albumin and haemoglobin.
RESULTS: The Mean (SD) weight gain at 3 months was higher in the RUTF group: RUTF (n=51): 0.54 kg; (SE = 0.05; 95% CI = 0.44 - 0.65) vs HCCM (n=45): 0.38 kg;(SE = 0.06; 95% CI = 0.25 - 0.51), P = 0.047. The weight gain per kilogram of body weight was directly proportional to the severity of malnutrition.
CONCLUSIONS: Community-based treatment showed weight gain in both groups, the gain being higher with RUTF.
Azara Sneha Singh; Gagandeep Kang; Anup Ramachandran; Rajiv Sarkar; Pearline Peter; Anuradha Bose
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Indian pediatrics     Volume:  47     ISSN:  0974-7559     ISO Abbreviation:  Indian Pediatr     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-10-25     Completed Date:  2011-03-01     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  679-86     Citation Subset:  IM    
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MeSH Terms
Child, Preschool
Dietary Supplements*
Food, Formulated*
Food, Fortified*
Malnutrition / diet therapy*
Nutrition Therapy / methods*

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