Document Detail

Localized lesions on MRI in a case of hypertensive brainstem encephalopathy.
MedLine Citation:
PMID:  16258222     Owner:  NLM     Status:  MEDLINE    
We report a case of hypertensive brainstem encephalopathy (HBE) with unusual magnetic resonance imaging (MRI) findings. A 67-year-old woman presented with high blood pressure and stupor as the only symptoms. MRI revealed lesions localized in the area from the upper medulla oblongata to the lower pons with high fluid-attenuated inversion recovery (FLAIR) and T2-weighted signal intensity, but these were not seen in the whole brainstem and there were no accompanying occipital lobe changes. To our knowledge, no similar case has been reported. The lesions and symptoms dramatically improved after normalization of blood pressure. Severe hypertension that exceeded the range of autoregulation may have resulted in segmental vasodilatation and the increased vascular permeability may have lead to vasogenic edema in the localized areas of the brainstem.
Yoichi Ono; Yasuhiro Manabe; Yoshiyuki Hamakawa; Tetsuro Murakami; Nobuhiko Omori; Yasuaki Hayashi; Koji Abe
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  44     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-10-31     Completed Date:  2006-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1002-5     Citation Subset:  IM    
Department of Neurology, National Hospital Organization Okayama Medical Center, Japan.
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MeSH Terms
Antihypertensive Agents / therapeutic use
Brain Stem / pathology*
Hypertensive Encephalopathy / diagnosis,  drug therapy,  etiology,  pathology*
Magnetic Resonance Imaging
Tomography, Emission-Computed, Single-Photon
Reg. No./Substance:
0/Antihypertensive Agents

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