Document Detail


Localized interstitial pulmonary amyloid: a case report and review of the literature.
MedLine Citation:
PMID:  19465854     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: Diffuse interstitial pulmonary amyloidosis is a fatal disorder that is rare and often undiagnosed. There are many documented cases of diffuse interstitial amyloid occurring with systemic amyloid light-chain amyloid. We present an extraordinary case of localized interstitial amyloidosis, making our case the eleventh documented in the literature. RECENT FINDINGS: We review the subtypes of tracheobronchial-pulmonary amyloidosis and their clinical presentations. There is also a thorough investigation of the literature published on localized diffuse interstitial pulmonary amyloid, and we provided information on the recent advances in treatment and diagnosis of amyloid. SUMMARY: Although localized diffuse interstitial amyloid is a rare finding, it is often not placed in the differential diagnosis, leading to the diagnosis being made at autopsy. With the use of new techniques and fiberoptic bronchoscopy an early diagnosis can be made. More research needs to be dedicated to the advancement of treatment for this fatal disease.
Authors:
Ayana BoydKing; Om Sharma; Kerry Stevenson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Current opinion in pulmonary medicine     Volume:  15     ISSN:  1531-6971     ISO Abbreviation:  Curr Opin Pulm Med     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-07-28     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503765     Medline TA:  Curr Opin Pulm Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  517-20     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Southern California, Los Angeles, California 90033, USA.
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MeSH Terms
Descriptor/Qualifier:
Amyloidosis / diagnosis*,  drug therapy
Biopsy
Bronchoscopy
Diagnosis, Differential
Female
Glucocorticoids / therapeutic use
Humans
Lung Diseases, Interstitial / diagnosis*,  drug therapy
Middle Aged
Radiography, Thoracic
Chemical
Reg. No./Substance:
0/Glucocorticoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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