Document Detail


Localized current field heating as an adjunct to radiation therapy.
MedLine Citation:
PMID:  7443977     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this paper is to report the results of a pilot study using hyperthermia as an adjunct to radiation therapy in the treatment of malignant disease, spontaneously occurring in domestic animals. Localized current fields (LCF) have been used to produce the hyperthermia. The aim of the pilot study was to establish a reasonable dose regime for testing in a randomized trial. The doses tested ranged from an equivalent 3,000 rads in 3 weeks to 6,000 rads in 6 weeks for the radiation treatments and 43 degrees C for 30 min to 45 degrees C for 30 min for the hyperthermia treatments. To date, there have been either complete or partial (over 50% tumor regression) responses in 82.9% of the animals and complete regression in 54.3% of the tumors. The details of the randomized trial are described.
Authors:
W G Connor
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Radiation and environmental biophysics     Volume:  17     ISSN:  0301-634X     ISO Abbreviation:  Radiat Environ Biophys     Publication Date:  1980  
Date Detail:
Created Date:  1981-02-24     Completed Date:  1981-02-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0415677     Medline TA:  Radiat Environ Biophys     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  219-28     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cat Diseases / radiotherapy,  therapy*
Cats
Dog Diseases / radiotherapy,  therapy*
Dogs
Hot Temperature / therapeutic use*
Methods
Neoplasms / radiotherapy,  therapy,  veterinary*
Pilot Projects
Remission, Spontaneous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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