Document Detail


Localized amyloid in thyroid: are we missing it?
MedLine Citation:
PMID:  23232573     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
When present in thyroid, amyloid is an attribute almost always restricted to medullary thyroid carcinoma. Scant studies in the literature have demonstrated this finding in other thyroid pathologies as papillary thyroid carcinoma, amyloid goiter, and other benign entities. From our experience in thyroid pathology, we analyzed cases on which the stroma contained deposits of amorphous, acellular, and eosinophilic material characteristic of amyloid. Congo red stain on suspicious cases was performed; clinicopathologic investigation was done when results were positive. Seven patients with amyloid infiltration in the thyroid, in association with papillary thyroid carcinoma, and in 4 cases of benign pathologies were found in our own review. The association of amyloid and thyroid is discussed herein, including cases of systemic amyloidosis, malignancies, benign diseases, and thyroid goiter, from our practice and from the available literature.
Authors:
André Pinto; Vânia Nosé
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in anatomic pathology     Volume:  20     ISSN:  1533-4031     ISO Abbreviation:  Adv Anat Pathol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9435676     Medline TA:  Adv Anat Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  61-7     Citation Subset:  IM    
Affiliation:
Department of Pathology, University of Miami Hospital, University of Miami Miller School of Medicine, Miami, FL.
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