| Localization of monoamine oxidases A and B in primate brains relative to neuron-specific and non-neuronal enolases. | |
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MedLine Citation:
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PMID: 7121716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using serotonin and phenylethylamine deamination as measures of MAO A and MAO B activity respectively, positive correlations were observed between the activities of MAO A and MAO B in different areas of rhesus monkey and human brains. When the activities of MAO A and MAO B were compared with those of neuron-specific enolase and nonneuronal enolase (isozymes which are markers for neurons and glia), a slight but non-significant correlation was observed, suggesting that a simple distribution of MAO A in neurons and MAO B in glia is unlikely. This conclusion is supported by studies using synaptosomes, but contrasts with that from investigations of MAO from peripheral tissues, where experiments indicate that MAO A is predominantly localized in neurones. |
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Authors:
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I C Campbell; P J Marangos; A Parma; N A Garrick; D L Murphy |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Neurochemical research Volume: 7 ISSN: 0364-3190 ISO Abbreviation: Neurochem. Res. Publication Date: 1982 Jun |
Date Detail:
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Created Date: 1982-12-02 Completed Date: 1982-12-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7613461 Medline TA: Neurochem Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 657-66 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain / enzymology* Cercopithecus aethiops Humans Macaca mulatta Monoamine Oxidase / metabolism* Neurons / enzymology* Phosphopyruvate Hydratase / metabolism* Species Specificity Tissue Distribution |
| Chemical | |
Reg. No./Substance:
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EC 1.4.3.4/Monoamine Oxidase; EC 4.2.1.11/Phosphopyruvate Hydratase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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