Document Detail


Localization of leukemia inhibitory factor in human endometrium during the menstrual cycle.
MedLine Citation:
PMID:  9363198     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Leukemia inhibitory factor (LIF) has been shown to be imperative for the implantation of mouse blastocysts. The objective of this study was to examine the pattern of LIF protein in the human endometrium during the menstrual cycle. A low level of LIF was detected in endometrial glands during the proliferative phase. During the luteal phase, LIF staining in the glands appeared stronger in the mid- and late luteal phase than immediately after ovulation. However, a low level of LIF was detected in the stromal cells during the early and midproliferative phase, while only a minimal level was observed during the late proliferative and luteal phases.
Authors:
Z M Yang; D B Chen; S P Le; R W Brown; C J Chuong; M J Harper
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy     Volume:  2     ISSN:  1354-4195     ISO Abbreviation:  Early Pregnancy     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1997-12-04     Completed Date:  1997-12-04     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9508879     Medline TA:  Early Pregnancy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  18-22     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Biopsy
Endometrium / chemistry*,  metabolism
Female
Fluorescent Antibody Technique, Direct
Growth Inhibitors / analysis*,  immunology,  metabolism
Humans
Hysterectomy
Immune Sera / immunology
Immunohistochemistry
Interleukin-6*
Leukemia Inhibitory Factor
Lymphokines / analysis*,  immunology,  metabolism
Menstrual Cycle / metabolism*
Mice
Middle Aged
Rabbits
Grant Support
ID/Acronym/Agency:
HD 07495/HD/NICHD NIH HHS; HD 14048/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Growth Inhibitors; 0/Immune Sera; 0/Interleukin-6; 0/LIF protein, human; 0/Leukemia Inhibitory Factor; 0/Lif protein, mouse; 0/Lymphokines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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