Document Detail

Localization of the initial fibrillatory cycle in patients with paroxysmal atrial fibrillation.
MedLine Citation:
PMID:  11759122     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Recent reports suggest the presence of conduction delay in the posterior septal region during sinus rhythm in patients with lone paroxysmal atrial fibrillation (AF). OBJECTIVE: To explore the location of intra-atrial conduction delay associated with initiation of AF. DESIGN: In 8 lone AF patients (51 +/- 10 years), 20 AF paroxysms were induced during electrophysiological examination. Bipolar electrograms were acquired from a 10-polar catheter in the coronary sinus (CS), a 4-polar His bundle catheter, and a 20-polar Halo catheter in the right atrium. RESULTS: Induced AF paroxysms showed earliest registered atrial activity in interatrial septum (IAS) or proximal CS in 17 cases (85%). Conduction delay at the posterior IAS or proximal CS accompanied induction of 18 AF paroxysms (6 patients). Atrial activation sequence at the beginning of the AF paroxysms was stable and reproducible in six repeatedly induced AF episodes (3 patients). CONCLUSION: In lone AF patients, induction of AF is associated with conduction disturbances in the IAS and proximal CS regions.
P G Platonov; S Yuan; E Hertervig; Kongstad; L V Chireikin; S B Olsson
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian cardiovascular journal : SCJ     Volume:  35     ISSN:  1401-7431     ISO Abbreviation:  Scand. Cardiovasc. J.     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-12-07     Completed Date:  2002-03-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9708377     Medline TA:  Scand Cardiovasc J     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  270-9     Citation Subset:  IM    
Department of Cardiology, Lund University, Sweden.
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MeSH Terms
Atrial Fibrillation / physiopathology*
Atrial Function, Right / physiology
Electric Stimulation
Electrophysiologic Techniques, Cardiac
Heart Atria / physiopathology
Heart Conduction System / physiopathology*
Heart Septum / physiopathology
Middle Aged
Erratum In:
Scand Cardiovasc J 2001 Dec;35(6):415

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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