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Localization and identification of parapharyngeal metastases from differentiated thyroid carcinoma by (131) I-SPECT/CT.
MedLine Citation:
PMID:  20848436     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: Parapharyngeal metastasis is a rare event in differentiated thyroid carcinoma (DTC). The (131) I-single photon emission CT (SPECT)/CT allows better localization and definition for metastases in DTC. The aim of this study was to assess the value of (131) I-SPECT/CT for the diagnosis of parapharyngeal metastasis in patients with DTC.
METHODS: Consecutive patients with DTC (n = 561) treated with (131) I for the ablation of remnant or treatment of metastases were enrolled. A (131) I-SPECT/CT was performed when there were abnormal findings indicative of parapharyngeal metastasis on (131) I-whole-body scan (WBS).
RESULTS: A total of 15 lesions were found to be parapharyngeal metastasis in 14 of 561 patients with DTC after the use of (131) I-SPECT/CT. The incidence rate of parapharyngeal metastasis was about 2.5% in DTC. Of the 15 lesions, only 5 lesions were CT-positive. The remaining 10 lesions were either ignored or indeterminate by the CT alone.
CONCLUSION: The (131) I-SPECT/CT can identify parapharyngeal metastasis at an early stage. Parapharyngeal metastasis in DTC is relatively frequent after the use of (131) I-SPECT/CT. © 2010 Wiley Periodicals, Inc. Head Neck, 2011.
Authors:
Zhong-Ling Qiu; Yan-Hong Xu; Hong-Jun Song; Quan-Yong Luo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Head & neck     Volume:  33     ISSN:  1097-0347     ISO Abbreviation:  Head Neck     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  United States    
Other Details:
Languages:  eng     Pagination:  171-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Wiley Periodicals, Inc.
Affiliation:
Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, 600 Yishan Road, Shanghai 200233, China.
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