| Localization and differential expression of FMRFamide-like immunoreactivity in the nematode Ascaris suum. | |
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MedLine Citation:
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PMID: 8349852 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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By immunocytochemical and immunohistochemical methods, FMRFamide-like immunoreactivity (FLI) was localized to many neurons and processes in the Ascaris nervous system, including the head, tail, and lateral lines. Some of these cells were identified; they included sensory neurons, interneurons, and motor neurons. FLI was also present in the pharyngeal neurons and in their varicosities near the surface of the pharynx. By HPLC analysis of extracts, only a subset of the FMRFamide-like peptides (FLPs) expressed in Ascaris heads, and heads from which the pharynx had been removed, were expressed in the pharynx. Furthermore, FLPs appeared to be differentially expressed in female heads and tails and male heads and tails. Acetone and acid methanol differentially extracted subforms of FLI from Ascaris heads and from C. elegans. |
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Authors:
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C Cowden; P Sithigorngul; P Brackley; J Guastella; A O Stretton |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of comparative neurology Volume: 333 ISSN: 0021-9967 ISO Abbreviation: J. Comp. Neurol. Publication Date: 1993 Jul |
Date Detail:
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Created Date: 1993-09-10 Completed Date: 1993-09-10 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0406041 Medline TA: J Comp Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 455-68 Citation Subset: IM |
Affiliation:
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Department of Zoology, University of Wisconsin, Madison 53706. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Ascaris suum / metabolism* Chromatography, High Pressure Liquid FMRFamide Female Immunohistochemistry Invertebrate Hormones / metabolism Male Motor Neurons / metabolism Neurons / metabolism Neuropeptides / metabolism* Pharynx / innervation Radioimmunoassay Tissue Distribution |
| Grant Support | |
ID/Acronym/Agency:
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AI 15429/AI/NIAID NIH HHS; AI 20355/AI/NIAID NIH HHS; NS07954/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Invertebrate Hormones; 0/Neuropeptides; 64190-70-1/FMRFamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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