Document Detail

Localization of absorbers in scattering media by use of frequency-domain measurements of time-dependent photon migration.
MedLine Citation:
PMID:  20885744     Owner:  NLM     Status:  In-Data-Review    
Frequency-domain studies of time-dependent light propagation in tissuelike phantoms that contain optical heterogeneities are described. Specifically the phase shift and amplitude modulation of reemergent light were measured when illuminated by an amplitude-modulated light source. Changes in the phase angle and the extent of modulation revealed the presence of a light-absorbing object. Furthermore the magnitude and direction of these changes were sensitive to the absorber depth and the light modulation frequency in a manner that could be used to infer the location of the heterogeneity. These data suggest the feasibility of optical imaging by frequency-domain methods.
E M Sevick; J K Frisoli; C L Burch; J R Lakowicz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Applied optics     Volume:  33     ISSN:  0003-6935     ISO Abbreviation:  Appl Opt     Publication Date:  1994 Jun 
Date Detail:
Created Date:  2010-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0247660     Medline TA:  Appl Opt     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3562-70     Citation Subset:  -    
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