Document Detail

Localization of the 5' end of the MCF2 oncogene to human chromosome 15q15----q23.
MedLine Citation:
PMID:  1611909     Owner:  NLM     Status:  MEDLINE    
Oncogenic activation of the MCF.2 cell line-derived transforming sequence gene (MCF2) occurs through substitution of part of its 5' coding region by unrelated nonsyntenic sequences. Analysis of the MCF2 oncogene locus revealed complex recombination events involving four discontinuous human DNA segments. The upstream replacing sequence, named URS, represents the farthest 5' portion of the locus. The URS sequence maps to the D15S93 locus on human chromosome 15q15----q23.
F Galland; M Stefanova; M Lafage; D Birnbaum
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cytogenetics and cell genetics     Volume:  60     ISSN:  0301-0171     ISO Abbreviation:  Cytogenet. Cell Genet.     Publication Date:  1992  
Date Detail:
Created Date:  1992-07-29     Completed Date:  1992-07-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0367735     Medline TA:  Cytogenet Cell Genet     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  114-6     Citation Subset:  IM    
U.119 INSERM, Marseille, France.
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MeSH Terms
Base Sequence
Chromosomes, Human, Pair 15*
Molecular Sequence Data
Oncogenes / genetics*
Recombination, Genetic / genetics
Restriction Mapping

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