Document Detail

Localisation of carcinoembryonic antigen in embryonic and fetal human tissues.
MedLine Citation:
PMID:  6874415     Owner:  NLM     Status:  MEDLINE    
Carcinoembryonic antigen (CEA) was localized in various embryonic and fetal human tissues between 8 and 16 weeks of gestation as well as in the colorectal mucosa of older fetuses, newborns and adults. Among the embryonic tissues, CEA was always present in the esophagus, the gastric antrum, the duodenum and the rectum. CEA positive staining of bile canaliculi of the liver was inconstant. All other embryonic tissues were CEA negative. During early fetal development, CEA positive staining of the esophagus, antrum and duodenum was inconstant. However, the whole colon became intensively stained. An inconstant CEA specific staining was found in parts of the midgut and in the bile canaliculi of the liver. The other organs remained CEA negative. Between the 17th week of gestation and birth, CEA staining pattern of the colorectal mucosa did not change. The staining intensity of late fetal colonic mucosa was similar to that of adult colonic mucosa.
C Wagener; F Hain; H J Födisch; H Breuer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Histochemistry     Volume:  78     ISSN:  0301-5564     ISO Abbreviation:  Histochemistry     Publication Date:  1983  
Date Detail:
Created Date:  1983-09-23     Completed Date:  1983-09-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0411300     Medline TA:  Histochemistry     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  1-9     Citation Subset:  IM    
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MeSH Terms
Carcinoembryonic Antigen / analysis*
Colon / embryology,  immunology
Embryo, Mammalian / immunology*
Fetus / immunology*
Gestational Age
Rectum / embryology,  immunology
Tissue Distribution
Reg. No./Substance:
0/Carcinoembryonic Antigen

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