| Local treatment of psoriasis of the scalp with clobetasol propionate and betamethasone-17,21-dipropionate: a double-blind comparison. | |
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MedLine Citation:
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PMID: 795609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A double-blind evaluation was carried out in 40 patients with moderate to severe psoriasis of the scalp to assess the effectiveness of a 0.05% alcoholic solution of clobetasol propionate as compared with a 0.05% alcoholic solution of betamethasone-17,21-dipropionate. Patients were treated on a non-selective basis with a twice a day application for 2 weeks. When comparing the effects on the parameters scaling, induration, erythema and itching it was concluded that clobetasol propionate was superior to betamethasone-17,21-dipropionate as an antipsoriatic compound. Clobetasol propionate did not cause any side-effects, while 2 of the patients using betamethasone-17,21-dipropionate developed a forehead folliculitis during the second week of treatment. |
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Authors:
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A Lassus |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Current medical research and opinion Volume: 4 ISSN: 0300-7995 ISO Abbreviation: Curr Med Res Opin Publication Date: 1976 |
Date Detail:
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Created Date: 1977-03-21 Completed Date: 1977-03-21 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0351014 Medline TA: Curr Med Res Opin Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 365-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Betamethasone
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analogs & derivatives*,
therapeutic use* Clinical Trials as Topic Clobetasol / therapeutic use* Humans Psoriasis / drug therapy* Scalp Dermatoses / drug therapy* |
| Chemical | |
Reg. No./Substance:
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25122-41-2/Clobetasol; 378-44-9/Betamethasone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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