Document Detail


Local treatment of candidal vaginitis with a mepartricin-sodium lauryl sulfate complex.
MedLine Citation:
PMID:  3619978     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
44 patients with candidal vaginitis participated in a trial using a new formulation of a mepartricin-sodium lauryl sulfate complex for local administration (dosage schedule: one 25,000-unit vaginal tablet (SPA-S-222) daily for 6 days). Microbiological examination revealed an 88.6% cure rate (samples tested negative) at the end of treatment and a 90.9% cure rate 30 days after cessation of treatment. In addition, the clinical symptoms observed at the beginning of treatment disappeared rapidly and the patients showed great clinical improvement under the present therapy. Both local and systemic tolerance of the preparation used were excellent.
Authors:
P Godts
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arzneimittel-Forschung     Volume:  37     ISSN:  0004-4172     ISO Abbreviation:  Arzneimittelforschung     Publication Date:  1987 May 
Date Detail:
Created Date:  1987-09-21     Completed Date:  1987-09-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372660     Medline TA:  Arzneimittelforschung     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  577-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Intravaginal
Adult
Candidiasis, Vulvovaginal / drug therapy*,  microbiology
Female
Humans
Mepartricin / administration & dosage,  therapeutic use*
Middle Aged
Polyenes / therapeutic use*
Sodium Dodecyl Sulfate / administration & dosage,  therapeutic use*
Chemical
Reg. No./Substance:
0/Polyenes; 11121-32-7/Mepartricin; 151-21-3/Sodium Dodecyl Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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