Document Detail


Local and systemic effects on blood lactate concentration during exercise with small and large muscle groups.
MedLine Citation:
PMID:  16642364     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate the relationship between lactate release and [lac](art) and to investigate the influence of the catecholamines on the lactate release, 14 healthy men [age 25+/-3 (SE) year] were studied by superimposing cycle on forearm exercise, both at 65% of their maximal power reached in respective incremental tests. Handgrip exercise was performed for 30 min at 65% of peak power. In addition, between the tenth and the 22nd minute, cycling with the same intensity was superimposed. The increase in venous lactate concentration ([lac](ven)) (rest: 1.3+/-0.4 mmol.l(-1); 3rd min: 3.9+/-0.8 mmol.l(-1)) begins with the forearm exercise, whereas arterial lactate concentration ([lac](art)) remains almost unchanged. Once cycling has been added to forearm exercise (COMB), [lac](art) increases with a concomitant increase in [lac](ven) (12th min: [lac](art), 3.2+/-1.3 mmol.l(-1); [lac](ven), 5.7+/-2.2 mmol.l(-1)). A correlation between oxygen tension (P(v)O(2)) and [lac](ven) cannot be detected. There is a significant correlation between [lac](art) and norepinephrine ([NE]) (y=0.25x+1.2; r=0.815; p<0.01) but no correlation between lactate release and epinephrine ([EPI]) at moderate intensity. Our main conclusion is that lactate release from exercising muscles at moderate intensities is neither dependent on P(v)O(2) nor on [EPI] in the blood.
Authors:
R Chudalla; S Baerwalde; G Schneider; N Maassen
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2006-04-27
Journal Detail:
Title:  Pflügers Archiv : European journal of physiology     Volume:  452     ISSN:  0031-6768     ISO Abbreviation:  Pflugers Arch.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-01     Completed Date:  2007-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0154720     Medline TA:  Pflugers Arch     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  690-7     Citation Subset:  IM    
Affiliation:
Sports and Exercise Physiology, Medical School Hannover, Carl-Neubergstrasse 1, 30625 Hannover, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bicycling / physiology
Blood Gas Analysis
Exercise / physiology*
Forearm / physiology
Heart Rate / physiology
Humans
Lactic Acid / blood*
Male
Muscle, Skeletal / physiology*
Norepinephrine / blood
Oxygen / blood
Oxygen Consumption / physiology
Sympathetic Nervous System / physiology
Weight Lifting / physiology
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid; 51-41-2/Norepinephrine; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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